Most people think of histamine only when they’re dealing with allergies — that sneezing, itching, or runny nose that has them reaching for an antihistamine. But histamine is much more than that. It’s a natural compound that plays essential roles in the body, acting as a neurotransmitter in the brain, a regulator in the gut, a modulator of the immune system, and even an influencer of sleep and mood. Histamine itself isn’t the problem. The real issue is histamine overload - whe